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Hail: Scalable Genomics Analysis with Apache Spark ...
The first thing to do in Hail is load the data, typically from a VCF file, which is the industry standard file format for variant data. VCF is a text format, but Hail can load VCF files compressed with BGZF, a splittable extension of gzip that is commonly used in bioinformatics.
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Genomic Analysis with Hail on Amazon EMR and Amazon Athena ...
For this task, we use Hail, an open source framework for exploring and analyzing genomic data that uses the Apache Spark framework. In this post, we use Amazon EMR to run Hail. We walk through the setup, configuration, and data processing. Finally, we generate an Apache Parquet–formatted variant dataset and explore it using Amazon Athena.